Author

Alejandro Álvarez-Arce

Loyola University ChicagoORCID 0000-0001-9608-3004Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:differential expression· 1 Organism:rat· 1

Frequent Co-Authors

Alexandra PeñaiD· 2 shared David Y. BarefieldiD· 2 shared Hannah E. CizauskasiD· 2 shared Hope V. BurnhamiD· 2 shared Kelly AraujoiD· 2 shared Azaria Panni· 1 shared Christine E. DelligattiiD· 1 shared Geena E. FritzmanniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersPhysiology

Alexandra PeñaORCID

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2 papers

Recent·Most cited

PhysiologyThe Journal of General PhysiologyPeer-reviewedSep 23, 2025

MYBPHL nonsense mutations have poor sarcomere binding, are degraded, and cause abnormal contraction

Alejandro Álvarez-Arce, Geena E. Fritzmann, Hope V. Burnham…·David Y. Barefield

The paper investigates MYBPHL nonsense mutations, showing they impair sarcomere incorporation, lead to protein degradation, and cause contractile defects in cardiomyocytes.

2 citations

ratproteomics

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Cell BiologyAmerican Journal of Physiology-Heart and Circulatory PhysiologyPeer-reviewedJun 28, 2024

Proteolytic degradation of atrial sarcomere proteins underlies contractile defects in atrial fibrillation

Hannah E. Cizauskas, Hope V. Burnham, Azaria Panni…·David Y. Barefield

This study identifies proteolytic degradation of atrial sarcomere proteins as a mechanism underlying contractile defects in atrial fibrillation.

10 citations

proteomicsexperimental assay

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