Cancer BiologyScience AdvancesPeer-reviewed
Generative Adversarial Networks Accurately Reconstruct Pan-Cancer Histology from Pathologic, Genomic, and Radiographic Latent Features
Frederick Matthew Howard, Hanna M. Hieromnimon, Siddhi Ramesh…·Alexander T. Pearson
This paper introduces HistoXGAN, a GAN that reconstructs cancer histology from latent features, showing it retains tumor grade, histologic subtype, and gene expression patterns across 29 cancer types.
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