BiochemistryScientific ReportsPeer-reviewed
Determining the defining lengths between mature microRNAs/small interfering RNAs and tinyRNAs
GeunYoung Sim, Audrey C. Kehling, Mi Seul Park…·Kotaro Nakanishi
The paper determines the minimum guide lengths required for miR-20a and let-7a to maintain their RISC conformation, finding 19 and 20 nt respectively, and identifies 17-nt guides as functional tinyRNAs (tyRNAs) without PAZ domain anchoring.
17 citations