Author

Audrey C. Kehling

The Ohio State UniversityORCID 0000-0003-2160-173XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1

Frequent Co-Authors

Cameron DivokyiD· 2 shared GeunYoung SimiD· 2 shared Huaqun ZhangiD· 2 shared Jackson SecoriD· 2 shared Kotaro NakanishiiD· 2 shared Mi Seul ParkiD· 2 shared Nipun MalhotraiD· 2 shared Divyaa BhagdikariD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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2 shared papersBiochemistry

Cameron DivokyORCID

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2 papers

Recent·Most cited

BiochemistryScientific ReportsPeer-reviewedNov 13, 2023

Determining the defining lengths between mature microRNAs/small interfering RNAs and tinyRNAs

GeunYoung Sim, Audrey C. Kehling, Mi Seul Park…·Kotaro Nakanishi

The paper determines the minimum guide lengths required for miR-20a and let-7a to maintain their RISC conformation, finding 19 and 20 nt respectively, and identifies 17-nt guides as functional tinyRNAs (tyRNAs) without PAZ domain anchoring.

17 citations

experimental assay

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Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewedDec 12, 2022

Manganese-dependent microRNA trimming by 3'->5' exonucleases generates 14-nucleotide or shorter tiny RNAs

GeunYoung Sim, Audrey C. Kehling, Mi Seul Park…·Kotaro Nakanishi

The paper identifies manganese-dependent 3'->5' exonucleases that trim miRNAs to generate short tyRNAs, revealing their role in AGO3 slicer activity and gene silencing under stress conditions.

27 citations

humanexperimental assay

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