Colt D. Capan

This study shows that tau filament seeding capacity depends on both core structure and phosphorylation in the fuzzy coat, with phospho-mimetic residues restoring activity in modified tau.

This study identifies glucose-dependent glycosphingolipid biosynthesis as essential for CD8+ T cell expansion and tumor control, independent of energy production.

The paper identifies a role for oocyte mitochondrial electron transport chain remodeling in linking maternal environment to offspring metabolism and survival.

The paper shows that metabolite extracts contain active enzymes and demonstrates a new workflow to remove proteins for improved metabolomics.

The paper finds increased levels of neurotoxic metabolites in mild COVID-19 patients, associated with inflammation and hypertension.