Author
University of California San DiegoORCID 0000-0001-9675-3071Unclaimed ORCID profile · follow to get notified of new preprints
8 papers
Recent·Most cited
Philip J. Freda, Attri Ghosh, Elizabeth Zhang…·Jason H. Moore
AutoQTL automates QTL analysis and GWAS by applying machine learning to detect both additive and non-additive genetic effects in genetic data.
Samuel Fowler, Tengfei Wang, Daniel B. Munro…·Monica M. Jablonski
This study performs a GWAS in HS rats to identify genetic loci associated with intraocular pressure, finding three genome-wide significant loci and five candidate genes, including novel ones.
Apurva S. Chitre, Oksana Polesskaya, Daniel B. Munro…·Abraham A. Palmer
The paper simulates GWAS in rats to show that larger sample sizes lead to an exponential increase in the number of significant loci detected.
Daniel B. Munro, Tengfei Wang, Apurva S. Chitre…·Pejman Mohammadi
The paper identifies cis-QTLs and eQTLs in HS rats across five brain regions, finds colocalization with human GWAS results, and shows higher eQTL density compared to human data.
Mustafa Hakan Gunturkun, Tengfei Wang, Apurva S. Chitre…·Hao Chen
This study identifies 30 genome-wide significant QTLs for open field behaviors in rats, with 13 candidate genes linked to psychiatric disorders in humans.
Apurva S. Chitre, Oksana Polesskaya, Katie Holl…·Leah C. Solberg Woods
Alexander F. Gileta, Jianjun Gao, Apurva S. Chitre…·Abraham A. Palmer
The paper adapts genotype-by-sequencing for HS rats to call and impute over 3.7 million SNPs with 99% concordance compared to a genotyping array.
Dayana A. Delgado, Chenan Zhang, Kevin J. Gleason…·Brandon L. Pierce
The paper estimates the contribution of direct telomere inheritance from parents to offspring to the heritability of leukocyte telomere length in humans.