Cancer BiologyNaturePeer-reviewed
Neuronal substance-P drives breast cancer growth and metastasis via an extracellular RNA/TLR7 axis
Veena Padmanaban, Isabel Keller, Ethan S. Seltzer…·Sohail F. Tavazoie
This study identifies neuronal substance-P as a driver of breast cancer growth and metastasis through an extracellular RNA/TLR7 signaling axis, with therapeutic targeting showing efficacy in mouse models.
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