Author

Jiazhen Xu

University of PittsburghORCID 0000-0001-9692-0343Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Organism:yeast· 1

Frequent Co-Authors

Aaron C. WacholderiD· 1 shared Alessandra ChesiiD· 1 shared Amanda M. GleixneriD· 1 shared Anastasia C. MurthyiD· 1 shared Andrew P. VanDemarkiD· 1 shared Anne‐Ruxandra CarvunisiD· 1 shared Ashleigh SmirnoviD· 1 shared Bede PortziD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Aaron C. WacholderORCID

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2 papers

Recent·Most cited

BiochemistryMolecular CellPeer-reviewedJan 1, 2026

Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains

Lin Guo, Jacob R. Mann, Jocelyn C. Mauna…·James Shorter

The paper identifies short RNAs that prevent and reverse pathological fibrillization of RNA-binding proteins like FUS and TDP-43, showing therapeutic potential for ALS/FTD.

25 citationstop 1%

humanbulk RNA-seq

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Molecular BiologybioRxivPreprintJan 19, 2022

On the illusion of auxotrophy: met15Δ yeast cells can grow on inorganic sulfur thanks to the previously uncharacterized homocysteine synthase Yll058w

S. Branden Van Oss, Saurin Bipin Parikh, Nelson Castilho Coelho…·Anne‐Ruxandra Carvunis

The paper shows that yeast cells lacking Met15 can assimilate inorganic sulfur via Yll058w, but require exogenous methionine or hydrogen sulfide chelators to grow, challenging the traditional view of MET15 as essential for sulfur assimilation.

5 citations

yeaststatistical model

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