Ravindra K. Gupta

This study shows that elderly individuals vaccinated against SARS-CoV-2 maintain neutralizing antibodies against recent variants, with reduced immune imprinting from ancestral variants after booster doses.

The paper analyzes over 3000 SARS-CoV-2 sequences from chronic infections to identify mutation patterns linked to viral persistence and long Covid.

This study investigates the B-cell response to transient HIV viraemia in elite controllers, revealing TLM heterogeneity and the role of innate-like B cells.

The paper identifies a mutation P812S in SARS-CoV-2 associated with immune evasion and upper airway adaptation, but reduced syncytia formation.

This study analyzes within-host SARS-CoV-2 evolution in chronic infections, finding variable rates of evolution and evidence of subpopulation structure.

The paper shows that CD4 T cell contact induces macrophage cell cycle progression from G0 to G1, increasing their susceptibility to lentiviral transduction.

This study shows hypoxia induces HIF2-dependent cell cycle entry in macrophages, leading to increased susceptibility to lentiviral transduction and is observed in tumor-associated macrophages.

This study investigates how N354 glycosylation in the SARS-CoV-2 spike protein affects viral fitness and human adaptation through multiple mechanisms.

The paper isolates a broadly neutralizing HIV-1 antibody from an untreated HIV-1 patient and shows memory B cells remain functional despite viral infection.

The paper analyzes resistance to dolutegravir in HIV patients in Nigeria, finding low-level resistance with one case of high-level resistance.

The paper investigates the origin of HIV in the CNS of ART-suppressed individuals and finds T cell-derived HIV that can lead to drug resistance.