Edward A A Fisher

This study shows that GRP170 protects podocytes from stress-induced glomerular injury by modulating the UPR, as demonstrated in a podocyte-specific knockout mouse model.

This study shows FITM2 deficiency reduces VLDL triglyceride secretion and causes ER stress and lipid accumulation in liver cells and mice.

This paper shows that cholesterol-loaded vascular smooth muscle cells (VSMCs) lose TGFβ signaling and contractile features, but HDL-mediated cholesterol efflux restores signaling and contractile markers.

This study shows colchicine stabilizes atherosclerotic plaques by converting harmful SMC-derived cells into protective myofibroblast-like cells, independent of its anti-inflammatory effects.

This study identifies CHREBP and NF-kappa B as regulators of ACSL1 expression in macrophages under hyperglycemia and inflammation.

The paper shows that loss of PRMT2 in myeloid cells impairs atherosclerosis regression in normoglycemic mice, mimicking diabetic conditions, through increased inflammation and macrophage dysfunction.

This study shows that inhibiting LXRα phosphorylation in hematopoietic cells reduces inflammation and improves atherosclerosis and obesity by altering macrophage and adipose tissue gene expression.

ExSeq enables multiplexed RNA mapping at nanoscale resolution by expanding biological specimens for in situ sequencing.

This study shows that phosphorylation of LXRα affects atherosclerosis regression by altering macrophage trafficking in diabetic mice.