Wulf Blankenfeldt

This study investigates the ability of SAM-dependent enzymes to accept D-SAM instead of L-SAM, finding that several enzymes can utilize D-SAM and highlighting implications for enzyme engineering.

This paper shows AcrVIB1 inhibits CRISPR-Cas13b by promoting unproductive crRNA binding and degradation, revealing a mechanism to suppress immune defense.

This paper identifies PrdH as the maturation enzyme required for the formation of the pyruvoyl group in the proline reductase Prd of C. difficile, essential for proline utilization and toxin production.

This paper identifies M35 as a viral protein that binds DNA and inhibits IRF3-mediated gene expression, including Ifnb1, thereby suppressing the antiviral type I IFN response.