Locus coeruleus degeneration is associated with cortical tau deposition and cognitive decline in older adults at familial risk of Alzheimer's disease
Alfie R. Wearn, Kate M. Onuska, Hayley R. C. Shanks…·R. Nathan Spreng
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Centre National de la Recherche ScientifiqueORCID 0000-0001-9983-5873Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Alfie R. Wearn, Kate M. Onuska, Hayley R. C. Shanks…·R. Nathan Spreng
J. Pérot, Anthony Ruze, Rahul Gaurav…·Stéphane Lehéricy
The paper uses NM-sensitive MRI to study neuromelanin accumulation and neurodegeneration in Parkinson's disease models, finding a biphasic signal change linked to a pathogenic threshold.
J. Pérot, Esther Kozlowski, Audrey Fraysse…·Stéphane Lehéricy
This study investigates network alterations in olfactory dysfunction in Parkinson's disease and iRBD patients using multimodal MRI, finding correlations between olfactory function and specific brain regions and networks.