Native and engineered human megakaryocytic extracellular vesicles for targeted non-viral cargo delivery to blood stem cells
Samik Das, Will Thompson, Eleftherios Terry Papoutsakis
This paper demonstrates that native and engineered human megakaryocytic extracellular vesicles can deliver non-viral cargo specifically to hematopoietic stem and progenitor cells, enhancing platelet production in mice.