Sha Sun

The paper identifies and quantifies leakage in single-cell benchmarks caused by group-owned answers and introduces a tool to assess this leakage before model training.

This study shows XIST modulates the adhesome network and cell stemness by altering adhesion pathways and gene expression in ovarian cancer cells and across tissues.

This paper develops a species-native representation for Xenopus laevis to compare regenerative competence across species and identifies a vector competence ruler that distinguishes regenerative from fibrotic repair in mice.

This study identifies robust Xist expression in male Peromyscus leucopus somatic cells, showing gene-selective repression rather than global X-chromosome inactivation.

The paper introduces gateway analysis to identify rare transient cell states at fate transitions in single-cell atlases and finds it detects previously missed molecular programs.

This paper develops a reaction-diffusion model to explain the spatial control of gene silencing during X chromosome inactivation, showing how feedback loops and chromatin modifications regulate the spread of silencing.

DistortCorrect Stitcher improves microscopy image stitching by integrating optical distortion correction, enhancing alignment accuracy for spatial transcriptomics data.

The paper investigates the functional conservation of lncRNA JPX across species despite sequence and structural divergence, showing it can functionally complement Jpx in mouse cells.