NeurosciencebioRxivPreprint
Amyloid-beta and tau pathologies are both necessary to induce novel stage-specific microglia subtypes during Alzheimer's disease progression.
Dong Won Kim, Kevin J. Tu, Alice Wei…·Tong Li
The paper identifies stage-specific microglia subtypes in Alzheimer's disease using single-cell RNA-sequencing, showing both amyloid-beta and tau pathologies are required for their induction.