Author

Chen Shen

Edinburgh Royal InfirmaryORCID 0000-0002-0119-4455Unclaimed ORCID profile · follow to get notified of new preprints

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Chen Shen4 papers · Case Western Reserve University

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Pharmacology & Toxicology· 1

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Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew Mark McIntoshiD· 1 shared Eleanor DavysoniD· 1 shared Mark J. AdamsiD· 1 shared Matthew H. IvesoniD· 1 shared Sarah E. HarrisiD· 1 shared Simon R. CoxiD· 1 shared Xueyi SheniD· 1 shared

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2026-2026 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

Andrew Mark McIntoshORCID

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1 paper

Recent·Most cited

Pharmacology & ToxicologyClinical EpigeneticsPeer-reviewedApr 22, 2026

The linear and non-linear effects of CYP2C19 metaboliser status on DNA methylation: a methylome-wide association study

Chen Shen, Mark J. Adams, Eleanor Davyson…·Xueyi Shen

This study investigates how CYP2C19 metaboliser status affects DNA methylation across the genome, finding 48 CpG sites associated with both linear and non-linear effects, linked to drug metabolism and inflammation.

1 citation

humanDNA methylation

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