Silke Braune

This study uses advanced imaging techniques to clarify SUN5's localization and dynamics during spermiogenesis, resolving previous controversies about its structure and function.

This study maps the luminal proteome of the ER and Golgi in T. brucei using TurboID proximity biotinylation, identifying TbMANF as a novel modulator of ER stress tolerance in African trypanosomes.

This study characterizes the trypanosome mRNA decapping enzyme ALPH1, showing it preferentially cleaves non-m7G-capped RNAs and produces diphosphate-RNA.

The paper uses expansion microscopy and proximity labeling to reveal an asymmetric nuclear pore structure in trypanosomes, identifying unique and conserved components involved in mRNA export.

This paper demonstrates that streptavidin-based imaging outperforms immunofluorescence in detecting low-abundance or inaccessible proteins and reveals dynamic protein interactions.