Susanne Krämer

This study maps the luminal proteome of the ER and Golgi in T. brucei using TurboID proximity biotinylation, identifying TbMANF as a novel modulator of ER stress tolerance in African trypanosomes.

This study characterizes the trypanosome mRNA decapping enzyme ALPH1, showing it preferentially cleaves non-m7G-capped RNAs and produces diphosphate-RNA.

This study shows that Trypanosoma brucei lacks a functional EJC and NMD pathway due to intron loss and gene redundancy.

The paper uses expansion microscopy and proximity labeling to reveal an asymmetric nuclear pore structure in trypanosomes, identifying unique and conserved components involved in mRNA export.

The paper identifies two distinct eIF4F complexes in Trypanosoma cruzi that bind different mRNAs and show altered associations under nutritional stress.

This paper demonstrates that streptavidin-based imaging outperforms immunofluorescence in detecting low-abundance or inaccessible proteins and reveals dynamic protein interactions.