NeuroscienceCell ReportsPeer-reviewed
Jedi-1/MEGF12-mediated phagocytosis controls the pro-neurogenic properties of microglia in the ventricular-subventricular zone
Vivianne E. Morrison, Matthew Houpert, Jonathan B. Trapani…·Bruce Douglas Carter
This paper shows that Jedi-1-mediated phagocytosis by microglia in the V-SVZ promotes neurogenesis by suppressing inflammatory pathways, and its loss leads to neuroinflammation and reduced neural precursor proliferation.
3 citations