Jessica L. Porter

This study develops a low-dose murine model of Mycobacterium ulcerans infection to analyze immune responses and identifies key cell types involved in disease progression.

This study investigates Buruli ulcer in possums in Victoria, Australia, finding M. ulcerans in 78% of clinically affected and 65% of non-lesioned possums, with lesions mapped and systemic bacterial dissemination observed.

The paper develops a low-cost DNA extraction method using paramagnetic beads for environmental surveillance of Mycobacterium ulcerans in possum excreta and tissue swabs, showing cost savings and comparable DNA quality to commercial kits.

This paper describes the discovery of a marine sponge-associated mycobacterium closely related to M. tuberculosis, which shares virulence factors but lacks virulence in mice.

This paper identifies M. ulcerans JKD8049 as a suitable human challenge strain for Buruli ulcer research due to its stability, antibiotic susceptibility, and ability to produce mycolactone.

This study uses bioluminescent Mycobacterium ulcerans in a mouse tail model to monitor Buruli ulcer progression and evaluate immune responses.

The paper develops a TaqMan qPCR assay for specific and rapid detection of M. chimaera DNA in clinical and environmental samples, showing higher sensitivity than culture methods.

The paper demonstrates that a low dose of Mycobacterium ulcerans can cause Buruli ulcer through skin punctures from mosquito bites or needles in mice.