Author

Lan H. Chu

University of WashingtonORCID 0000-0002-0378-6614Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:gene regulatory network inference· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

Andrew OberstiD· 2 shared Brian P. DanielsiD· 1 shared Daphnée M. MarciniakiD· 1 shared Emmanuelle GenoyeriD· 1 shared Joshua M. AmesiD· 1 shared Julian R. SmithiD· 1 shared Julie EggenbergeriD· 1 shared Katrina LichaucoiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Andrew OberstORCID

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2 papers

Recent·Most cited

ImmunologyScience SignalingPeer-reviewedApr 1, 2025

RIPK3 coordinates RHIM domain-dependent inflammatory transcription in neurons

Sigal B. Kofman, Lan H. Chu, Joshua M. Ames…·Andrew Oberst

This study shows RIPK3 drives antiviral transcription in neurons during ZIKV infection, while inducing cell death in MEFs, with RHIM domain interactions mediating these context-dependent functions.

12 citations

mouseexperimental assay

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ImmunologySciencePeer-reviewedDec 19, 2024

Cellular RNA interacts with MAVS to promote antiviral signaling

Nandan S. Gokhale, Russell K. Sam, Kim Y. Somfleth…·Ram Savan

The paper shows that cellular RNA interacts with MAVS to scaffold signaling proteins and promote antiviral signaling by facilitating IRF3 phosphorylation.

62 citationstop 1%

metagenomicsexperimental assay

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