Kiyoshi Kita

This study identifies new chemotypes that inhibit Plasmodium falciparum dihydroorotate dehydrogenase, revealing structural insights and potential for improved antimalarial drugs.

This study shows that PfDGAT is essential for Plasmodium falciparum survival by maintaining phospholipid homeostasis, regulating sexual differentiation, ER stress, and cytoadhesion.

This study identifies PfLPLAT1 as essential for Plasmodium falciparum cell cycle progression and cytostome function, with its deficiency causing developmental arrest and morphological changes.

This paper introduces a high-throughput screening method to identify fast-killing antimalarial compounds by measuring parasite reduction ratio using Plasmodium falciparum lactate dehydrogenase and fluorescent probes.