Rochelle L. Coulson

This study shows that ISRIB, a translational modulator, alleviates synaptic and behavioral issues in Fragile X syndrome by rescuing molecular and synaptic deficits in Fmr1 knockout mice.

The paper identifies epigenomic signatures in NDD cortex samples, revealing shared regulatory functions and enrichment for genetic risk factors across different NDD types.

The paper identifies two placental DNA methylation markers, CYP2E1 and IRS2, associated with ASD risk and modulated by genetic and environmental factors.

This study shows that Snord116 RNA processing requires an active endogenous allele and neuron-specific splicing by Rbfox3/NeuN, and exogenous expression alone cannot rescue the genetic deficiency of Snord116 paternal deletion.

This study identifies Snord116-dependent diurnal DNA methylation rhythms in mouse cortex and shows their disruption in Prader-Willi syndrome.

The paper investigates how augmented maternal care affects DNA methylation, gene expression, and miRNA levels in the developing hypothalamus, identifying genes linked to stress resilience.