Vural Tagal

This study models how resource limitations and chromosomal instability influence ploidy evolution in cancer cells across in vitro and in vivo settings.

This study shows that higher ploidy reduces gemcitabine potency and delays cell death by altering drug exposure kinetics and response timing.

The paper introduces CLONEID, a framework for organizing clone-resolved data to enable longitudinal genotype-to-phenotype mapping in experiments with repeated molecular and phenotypic measurements.

The paper integrates sequencing and imaging data to map cell cycle states, linking transcriptome states to living cells with high resolution.

This study uses a mathematical model to show that ploidy and resource availability in the tumor microenvironment influence glioblastoma initiation and recurrence.