Jackson P. Cole

This study shows that higher ploidy reduces gemcitabine potency and delays cell death by altering drug exposure kinetics and response timing.

The paper introduces CLONEID, a framework for organizing clone-resolved data to enable longitudinal genotype-to-phenotype mapping in experiments with repeated molecular and phenotypic measurements.

This study uses a mathematical model to show that ploidy and resource availability in the tumor microenvironment influence glioblastoma initiation and recurrence.