Author

Michael U. Musheev

Institute of Molecular BiologyORCID 0000-0002-0499-9689Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Christof NiehrsiD· 4 shared Amitava BasuiD· 2 shared Lars SchomacheriD· 2 shared Anke BuschiD· 1 shared Antje Ostareck‐LedereriD· 1 shared Bernhard LüscheriD· 1 shared Carola Scholz· 1 shared Christoph DieterichiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersBiochemistry

Christof NiehrsORCID

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4 papers

Recent·Most cited

BiochemistrybioRxivPreprintMar 31, 2026

Human PARPs modify RNA nucleobases in vitro and in cells

Michael U. Musheev, Jonas Siefert, Wiwik Bauten…·Roko Žaja

This study shows PARP10 and PARP15 modify RNA nucleobases in vitro and in cells, and TARG1 reverses these modifications.

DOI 10.64898/2026.03.31.715305

humanproteomics

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BiochemistrybioRxivPreprintDec 19, 2025

PARP1 Writes N3-Cytidine ADP-Ribosylation in DNA

Michael U. Musheev, Lars Schomacher, Johanna M. Schott…·Christof Niehrs

This study identifies PARP1's ability to ADP-ribosylate N3-deoxycytidine in ssDNA, leading to deamination products detectable by LC-MS/MS.

2 citations

DNA methylationexperimental assay

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Molecular BiologyNature CommunicationsPeer-reviewedOct 17, 2022

Mammalian N1-adenosine PARylation is a reversible DNA modification

Michael U. Musheev, Lars Schomacher, Amitava Basu…·Christof Niehrs

The paper demonstrates that mammalian DNA undergoes reversible N1-adenosine PARylation, identified through mass spectrometry and enzymatic analysis.

33 citations

humanDNA methylation

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GenomicsNucleic Acids ResearchPeer-reviewedJun 7, 2021

Deep and accurate detection of m6A RNA modifications using miCLIP2 and m6Aboost machine learning

Nadine Körtel, Cornelia Rücklé, You Zhou…·Kathi Zarnack

The paper improves m6A RNA modification detection using miCLIP2 and m6Aboost, identifying thousands of high-confidence sites in human and mouse cells without requiring Mettl3 depletion.

121 citationstop 2%

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