Haorong Li

This study identifies the CC2D1A interactome in human neurodevelopmental disorders, revealing synaptic roles and novel interactions in the brain.

The paper introduces ContamSPOT, a method to detect and remove trace contaminants in mass spectrometry samples using TLC plates, improving data quality and instrument longevity.

This study uses proteomic techniques to show that PGRN deficiency impairs lysosomal function and proteostasis in neurons by altering pH, enzyme levels, and protein turnover.

This study integrates proteomic and metabolomic analyses of patient-derived fibroblasts to identify dysregulated pathways in MELAS, revealing OXPHOS defects and arginine biosynthesis downregulation.