Karl Balabanian

This paper develops a 3D artificial marrow organoid model to study NK and myeloid cell differentiation, showing improved immune receptor expression and drug response compared to 2D models.

This study identifies CXCR4-expressing tumor-associated macrophages in bladder cancer and shows that targeting them improves immunotherapy outcomes in mice and patients.

This study identifies five plasma cell subsets in humans and mice, showing their heterogeneity is driven by immune challenge type and B cell origin.

This study shows that CXCR4 desensitization is crucial for regulating B cell activation, plasma cell differentiation, and migration in the extra-follicular response.