Author

Stephan Emmrich

University of RochesterORCID 0000-0002-0537-4242Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Developmental Biology· 3 Evolutionary Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 5 Assay:DNA methylation· 4 Research Focus:gene regulatory network inference· 4 Organism:human· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Vera A. GorbunovaiD· 4 shared Amin HaghaniiD· 3 shared Andrei SeluanoviD· 3 shared Caesar Z. LiiD· 3 shared Anna J. JasinskaiD· 2 shared Chris G. FaulkesiD· 2 shared D. Maddox· 2 shared Hippokratis KiarisiD· 2 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersDevelopmental Biology

Vera A. GorbunovaORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Evolutionary BiologyScience AdvancesPeer-reviewedJun 7, 2024

Epigenetic predictors of species maximum lifespan and other life history traits in mammals

Caesar Z. Li, Amin Haghani, T.R. Robeck…·L.B. Schook

The paper develops DNA methylation predictors for mammalian maximum lifespan, gestation time, and sexual maturity, showing species-level epigenetic signatures that differ from individual lifespan variation.

59 citationstop 3%

mousehuman

𝕏 PostBluesky

Developmental BiologyNature AgingPeer-reviewedAug 10, 2023

Universal DNA methylation age across mammalian tissues

Ake Tzu-Hui Lu, Zhe Fei, Amin Haghani…·June Mergl

The paper develops universal epigenetic clocks that accurately estimate age across mammalian tissues using DNA methylation data from 185 species.

396 citationstop 1%

mousehuman

𝕏 PostBluesky

Molecular BiologyThe EMBO JournalPeer-reviewedOct 10, 2022

A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A

Matthew A. Simon, Jiping Yang, Jonathan Gigas…·Vera A. Gorbunova

The paper identifies a SIRT6 variant enriched in centenarians that improves genome stability through enhanced mADPr activity and interaction with Lamin A.

73 citationstop 1%

humanDNA methylation

𝕏 PostBluesky

Developmental BiologybioRxivPreprintAug 1, 2021

An abundant myeloid progenitor shapes neonatal hematopoiesis of naked mole-rats

Stephan Emmrich, Alexandre Trapp, Andrei Seluanov, Vera Gorbunova

The paper identifies a unique myeloid progenitor cell type, TC90, specific to neonatal naked mole-rats that supports innate immunity during early development.

1 citation

bulk RNA-seqstatistical model

𝕏 PostBluesky

Developmental BiologybioRxivPreprintMar 15, 2021

DNA methylation clocks show slower progression of aging in naked mole-rat queens

Steve Horvath, Amin Haghani, Nicholas Macoretta…·Vera Gorbunova

This study develops DNA methylation clocks for naked mole-rats and finds that queens age more slowly than non-breeders, suggesting a link between reproductive status and epigenetic aging.

9 citations

DNA methylationstatistical model

𝕏 PostBluesky