Conserved folds enable immune antagonism across the tree of life
Lorenzo Profeta, Erin Doherty, Johanna M Ebner…·Jason Nomburg
The paper identifies conserved structural folds used by pathogens across all domains of life to evade immune responses.
Author
Icahn School of Medicine at Mount SinaiORCID 0000-0002-0602-2871Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
3 papers
Recent·Most cited
Lorenzo Profeta, Erin Doherty, Johanna M Ebner…·Jason Nomburg
The paper identifies conserved structural folds used by pathogens across all domains of life to evade immune responses.
Silva Kasela, Zharko Daniloski, Sailalitha Bollepalli…·Tuuli Lappalainen
The paper identifies SLC6A20 and CXCR6 as putative causal genes for the 3p21.31 GWAS signal in COVID-19 using an integrative approach combining CRISPR screens and eQTL data.
Zharko Daniloski, Tristan X. Jordan, Juliana K. Ilmain…·Neville E. Sanjana
The paper shows the D614G mutation in SARS-CoV-2 Spike protein increases infection efficiency in multiple human cell lines by enhancing proteolytic resistance.