Silvan Scheller

This study enables formate-dependent methanogenesis in Methanosarcina acetivorans through metabolic engineering and adaptive evolution, expanding its substrate utilization capabilities.

The paper measures methane and ethane production rates by methyl-coenzyme M reductase in cell extracts from various methanogens, finding higher ethane production rates than previously reported for purified enzymes.

The paper introduces tdFAST2:HBR-3,5DOM for flow cytometry in methanogens, enabling anaerobic fluorescence detection and high-throughput analysis of mixed cultures.

The paper introduces a CRISPR/Cas12a system for efficient genome editing in Methanosarcina acetivorans, enabling deletions, insertions, and multiplex edits with high success rates.