Atsushi Miyawaki

This paper introduces OxyBLI, a noninvasive optical method to monitor tissue oxygenation in real-time, showing how hypoxia and hyperoxia affect oxygen distribution in experimental animals.

FuChi is a new Fucci-based system in chickens that accurately tracks cell cycle phases in vivo, improving upon existing models by distinguishing all phases and enabling detailed developmental studies.

This study identifies myoclonin1's interaction with IP3 receptors and PRKCSH, showing it modulates ER-Ca2+ homeostasis, which may contribute to epilepsy in EFHC1 mutation carriers.

This paper introduces a synthetic near-infrared luciferin, AkaSuke, that enhances deep-tissue bioluminescence imaging with firefly luciferases by improving detection sensitivity.

The paper discovers a new form of cell-cell communication called DIVE, where vesicles are directly transferred between adjacent cells, potentially enabling nucleic acid exchange and phenotypic synchronization.

The paper identifies plaque-associated endogenous IgG in AD mouse models that interferes with immunohistochemical detection of mouse monoclonal IgG antibodies and shows that subclass-specific secondary antibodies can mitigate this issue.

This study compares three monomeric variants of StayGold to evaluate their photostability, brightness, and dispersibility, highlighting tradeoffs in fluorescent protein technology.

This study compares the photostability of StayGold with three other FPs under different illumination modes in microscopy, finding that StayGold maintains superior photostability in multi-beam LSCM but shows variable performance in single-beam LSCM.

The paper investigates how sensory signals are represented in the cerebellum by analyzing complex spikes in mouse brain segments.

This paper introduces a non-invasive in vivo imaging system to monitor neural graft activity after spinal cord injury and shows graft integration with host behavior.

The paper introduces FASHIO-2PM, a two-photon microscope that enables fast, aberration-free calcium imaging of large neural networks in awake mice at 7.5 Hz.

This paper demonstrates the manipulation of the optical refractive index in mammalian cells using cephalopod reflectin protein nanoparticles and shows their application in microscopy techniques.

The paper identifies a human segmentation clock by showing human PSM cells exhibit Notch and YAP-dependent oscillations of HES7 with a 5-hour period.