ImmunologyJournal of Clinical InvestigationPeer-reviewed
Sphingosine 1-phosphate receptor 1 inhibition induces a pro-apoptotic signaling cascade in T cells
Dhaval Dixit, Victoria M. Hallisey, Ethan Y.S. Zhu…·Susan R. Schwab
This study shows that S1PR1 inhibition leads to T cell apoptosis by altering BCL2 family balance and JNK activity, with implications for immune responses in ulcerative colitis.
29 citations