Pharmacology & ToxicologyBritish Journal of PharmacologyPeer-reviewed
SCA44- and SCAR13-associated GRM1 mutations affect metabotropic glutamate receptor 1 function through distinct mechanisms
Yuyang Wang, Ashwin Muraleetharan, Monica Langiu…·Shane D. Hellyer
This study investigates how specific mGlu1 mutations affect receptor function in SCA subtypes, revealing distinct mechanisms and potential therapeutic strategies using allosteric modulators.
7 citations