Monica Langiu

This study evaluates the pharmacological effects of mGlu5 allosteric modulators on human mGlu5, revealing species differences and implications for drug development.

This study investigates how specific mGlu1 mutations affect receptor function in SCA subtypes, revealing distinct mechanisms and potential therapeutic strategies using allosteric modulators.

This study shows that Gpr88 deletion increases motivational drive in both sexes and impairs cost/benefit decision making in males, without affecting striatal dopamine function.