Christopher J. Hernandez

This paper introduces mechanofiltration, a high-throughput method to measure bacterial cell mechanics using standard lab equipment, showing it accurately detects changes in cell stiffness across genetic and environmental conditions.

This study investigates how S. aureus traverses nanoscale channels in bone, finding that fluid pressure, not cell division, enables bacterial entry into narrow spaces.

Antibiotic disruption of the gut microbiome reduces heterotopic ossification in FOP mice via an IL-1 mediated pathway.

This paper shows that altering the gut microbiome changes bone matrix proteomics and reduces fracture toughness, with micropillar splitting as a precise method to measure these effects.

This study shows that MreB couples the cell wall to the cytoplasmic membrane in E. coli, increasing resistance to bending and preventing membrane detachment under stress.

The paper tracks antibiotic resistance gene (ARG) dynamics in mice during long-term antibiotic treatment, finding that commensal bacteria reduce ARG burden by outcompeting resistant taxa.

This study investigates the effects of menaquinone-9 (MK9) supplementation on bone health in mice, finding no significant impact on bone tissue quality or mineral density despite MK9 serving as a precursor to MK4 in bone.

The paper characterizes microbial differences in oyster reef ecosystems by analyzing abundance and diversity across soil, biofilm, and oysters in four sites, identifying distinct taxa and their associations with environmental factors.

This study shows that altering the gut microbiome in adult mice can reduce or restore bone matrix strength, with sex-specific effects.

The paper measures the Young's modulus of bacterial cell envelopes in E. coli, V. cholerae, and S. aureus using a microfluidic system and inverse finite element analysis, finding values ranging from 0.12 to 2.06 MPa.