Author

Rong-Guang Xu

Brigham and Women's HospitalORCID 0000-0002-0716-5831Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:multiple species· 1 Research Focus:phylogenetics / evolution· 1 Assay:protein sequence· 1 Approach:statistical model· 1

Frequent Co-Authors

Allan SuniD· 1 shared Atreyee Biswas· 1 shared Bari Chowdhury· 1 shared Christopher J. ZahneriD· 1 shared Fahad Mostafa· 1 shared Fangyuan ZhouiD· 1 shared Haoyi YangiD· 1 shared Heng Zhang· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioengineering

Allan SunORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintMay 1, 2026

From Generalist to Specialist: Evolution of PS2 α-integrins and Implications for Drug Targeting

Sun Shixi, Yunfeng Chen, Rong-Guang Xu…·Li Liu

The paper analyzes the evolutionary history of PS2-integrins across vertebrates to identify lineage-specific functional divergence and inform drug targeting strategies.

DOI 10.64898/2026.04.29.721650

multiple speciesprotein sequence

𝕏 PostBluesky

BioengineeringNature CommunicationsPeer-reviewedOct 21, 2024

Multi-parametric thrombus profiling microfluidics detects intensified biomechanical thrombogenesis associated with hypertension and aging

Misbahud Din, Souvik Paul, Sana Ullah…·Yunfeng Chen

This paper introduces a microfluidics-based thrombus profiling assay that detects intensified biomechanical thrombogenesis in hypertension and aging, revealing a GPIb-integrin mechanosensing axis hyperactivity mechanism.

26 citationstop 2%

humanexperimental assay

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