Author

Melanie R. Silvis

University of California, San FranciscoORCID 0000-0002-0732-9744Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Byoung‐Mo KooiD· 1 shared Cameron C. Hearne· 1 shared Carol A. GrossiD· 1 shared Hendrik OsadnikiD· 1 shared Horia TodoriD· 1 shared Jason M. PetersiD· 1 shared John S. Hawkins· 1 shared Jonathan S. WeissmaniD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperSystems Biology

Byoung‐Mo KooORCID

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1 paper

Recent·Most cited

Systems BiologyCell SystemsPeer-reviewedOct 19, 2020

Modulated efficacy CRISPRi reveals evolutionary conservation of essential gene expression-fitness relationships in bacteria

John S. Hawkins, Melanie R. Silvis, Byoung‐Mo Koo…·Carol A. Gross

The paper develops a CRISPRi system to modulate gene expression in bacteria and shows that essential gene expression-fitness relationships are conserved across species.

130 citationstop 3%

E. colimouse

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