Karin G. Stenkula

This paper develops a mathematical model of chylomicron dynamics incorporating the second meal effect, showing it can predict postprandial lipid responses across different BMI values.

This study shows that fixed-dose streptozotocin in HFD-fed mice induces a stable T2D-like phenotype, contrasting with weight-adjusted dosing which causes variability.

This paper develops a microfluidic device for sorting mature adipocytes by size, achieving high recovery, purity, and maintaining hormonal response.

The paper develops a mathematical framework to estimate insulin-stimulated glucose uptake per adipocyte, considering cell size dependence, and shows it slightly improves model-data agreement.

The paper develops a multi-scale digital twin model to simulate insulin resistance progression, validating it with diet and drug intervention data.

The paper presents an in silico mouse model that simulates multi-scale insulin resistance and type 2 diabetes progression across cells, organs, and the whole body.

This study tests the effects of four butyrate-producing bacteria on obesity and behavior in mice, finding one strain reduces obesity complications.