Priya Chudasama

This study identifies TRIM11 as a regulator of EWSR1::ATF1 stability in clear cell sarcoma, showing its depletion leads to metabolic rewiring and cell death, with PCK1 as a potential biomarker.

The paper identifies genomic and transcriptomic features of telomere maintenance mechanisms in complex karyotype sarcomas, linking ALT status to therapeutic vulnerabilities.

This paper develops a mouse model for high-risk sarcoma by delivering genetic lesions via electroporation, generating multiple sarcoma types and validating their molecular and therapeutic relevance.

This study identifies a DNA replication protein signature (SPM6) that improves risk stratification in soft tissue sarcomas when combined with the Sarculator nomogram.

The paper develops a computational framework to identify regulatory heterogeneity in leiomyosarcoma by analyzing gene regulatory networks and validates findings in independent datasets.