Chrystal Mary Paulos

The paper shows that confined T cell migration through pores reduces programmed cell death 1 expression via ubiquitin-mediated degradation, enhancing T cell function and correlating with disease outcomes in melanoma.

This study shows that neoantigen-reactive T cells achieve long-term antitumor effects through lymph node trafficking, enhancing their persistence and efficacy.

This study compares the effects of two host preconditioning methods on the antitumor activity of adoptively transferred Th17 cells, finding that total body irradiation enhances their efficacy more than chemotherapy.