Cell BiologybioRxivPreprint
Mechanical Stretch Kills Transformed Cancer Cells
Ajay Tijore, Mingxi Yao, Yu-Hsiu Wang…·Michael Sheetz
The paper shows that cyclic mechanical stretch induces apoptosis in transformed cancer cells but promotes growth in normal cells, with mechanoptosis driven by calcium influx and calpain activation.
DOI 10.1101/491746