Bowen Yu

The paper designs high-affinity mini-protein antagonists targeting IL-4Ra using deep learning, achieving improved binding affinity and in vivo stability comparable to existing therapies.

This study determines the structure of SCARF1 and identifies its ligand recognition mechanism, revealing key residues and shared binding sites for modified LDLs and bacterial teichoic acids.

Mocap predicts transcription factor binding sites using chromatin accessibility and genomic features, outperforming existing methods for new TF-cell-type combinations.