Author

Zhenxi Guo

Peking UniversityORCID 0000-0002-0872-0470Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Bin LiuiD· 1 shared Hang Hubert YiniD· 1 shared Heng ZhangiD· 1 shared Hong CheniD· 1 shared Hongtao WangiD· 1 shared Hongtao ZhuiD· 1 shared Jie HaniD· 1 shared Jie YangiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiochemistry

Bin LiuORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintSep 3, 2026

Nanocondensate tunnelling

Luyi Han, Yue Wan, Zhenxi Guo…·Yingyan Mao

This study observes nanocondensates tunneling through cellular membranes and demonstrates their ability to transport molecules across barriers.

DOI 10.64898/2026.06.22.731667

experimental assaydrug response / drug discovery

𝕏 PostBluesky

BiochemistryNature CommunicationsPeer-reviewedDec 7, 2025

Architecture and mechanism of a dual-enzyme retron system in prokaryotic immunity

Xuzichao Li, Qiuqiu He, Yanan Liu…·Heng Zhang

This study characterizes the Ec78 retron system, revealing its dual-enzyme effector complex and the molecular mechanism of phage clearance through cryo-EM structures and functional analysis.

8 citationstop 5%

bacteria (other)structural biology

𝕏 PostBluesky