Author

Gayan I. Balasooriya

Cold Spring Harbor LaboratoryORCID 0000-0002-0916-6686Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:differential expression· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

David L. SpectoriD· 2 shared Payal K. Naik· 1 shared Tse-Luen WeeiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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2 shared papersCell Biology

David L. SpectorORCID

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2 papers

Recent·Most cited

Cell BiologyCellular and Molecular Life SciencesPeer-reviewedJan 3, 2026

A sub-set of guanine- and cytosine-rich genes are actively transcribed at the nuclear Lamin B1 region

Gayan I. Balasooriya, Payal K. Naik, Tse-Luen Wee, David L. Spector

The paper identifies a subset of actively transcribed genes associated with Lamin B1 at the nuclear envelope in mESCs, showing enrichment of guanine and cytosine in their gene bodies and promoters.

DOI 10.1007/s00018-025-05976-3

mousebulk RNA-seq

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GenomicsNature CommunicationsPeer-reviewedOct 10, 2022

Allele-specific differential regulation of monoallelically expressed autosomal genes in the cardiac lineage

Gayan I. Balasooriya, David L. Spector

The paper investigates allele-specific regulation of monoallelically expressed autosomal genes in cardiac lineage cells, finding maternal allele dominance in cardiac development and homeostasis.

10 citations

mousescRNA-seq

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