Babatunde Ekundayo

This study shows that the inhibitor PBA binds to TRPM4 in different locations at 8°C and 37°C, revealing temperature-dependent changes in ligand recognition.

The paper introduces a robotic system for cryo-EM grid preparation that improves sample efficiency and reconstruction quality.

The paper determines the cryo-EM structure of alpha-synuclein fibrils with the E83Q mutation, revealing structural changes linked to enhanced aggregation and pathogenicity.

This study examines the host range and antigenicity of bat sarbecoviruses, finding that generalist ACE2 users are more related to SARS-CoV-2 and show broader cross-neutralization.

This study determines the structural basis of SIRT7's specificity for H3K36 and H3K18 deacylation by solving nucleosome-bound SIRT7 structures and analyzing enzyme-nucleosome interactions.

The paper identifies the binding site of small molecule inhibitors NBA and IBA in TRPM4 using cryo-EM and patch clamp experiments.