Author

Anamika Bhargava

Indian Institute of Technology HyderabadORCID 0000-0002-1048-3427Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Organism:Arabidopsis· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Ghazala RahmaniD· 2 shared Yashashwini Subbamanda· 2 shared Aarushi K Zinzuvadia· 1 shared Akarsh BajpaiiD· 1 shared Andrés Daniel MaturanaiD· 1 shared Atanu Pramanik· 1 shared Basant Kumar PateliD· 1 shared Eerappa RajakumaraiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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2 shared papersBiochemistry

Ghazala RahmanORCID

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4 papers

Recent·Most cited

BiochemistrybioRxivPreprintOct 19, 2026

Evolutionary plasticity of regulatory--catalytic coupling in mono- and poly-ADP-ribosyl transferases

Makwana Milee, Shambhavi Khare, Shanavas P Greeshma…·Eerappa Rajakumara

The paper investigates how regulatory and catalytic domains of ADP-ribosyltransferases co-evolve, showing functional complementarity across species and enzyme classes.

DOI 10.64898/2026.10.17.759577

humanArabidopsis

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Cancer BiologyJournal of Pharmaceutical and Biomedical AnalysisPeer-reviewedNov 1, 2025

Optimized LC-MS/MS method for Doxorubicin quantification: validating drug uptake and tumor reduction in zebrafish xenograft model of breast cancer

Ghazala Rahman, Atanu Pramanik, Susmita Das…·Anamika Bhargava

This study develops an LC-MS/MS method to quantify doxorubicin uptake in zebrafish larvae and determines its therapeutic effect in a breast cancer xenograft model.

DOI 10.1016/j.jpba.2025.117230

zebrafishexperimental assay

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BiochemistryChemical Biology & Drug DesignPeer-reviewedOct 1, 2024

In silico and in vitro studies suggest epigallocatechin gallate (EGCG), a polyphenol in green tea, can bind and modulate the aggregation and cytotoxicity of the full-length TDP-43 protein implicated in TDP-43 proteinopathies.

Vini D. Meshram, Ramkumar Balaji, Preethi Saravanan…·Basant Kumar Patel

This paper shows EGCG inhibits TDP-43 aggregation and cytotoxicity in vitro through binding to its C-terminal domain.

8 citations

humanprotein structure

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Cancer BiologybioRxivPreprintNov 16, 2023

Divergent outcomes of SAK3, a T-type calcium channel enhancer, in two luminal-A type breast cancer cell lines: T-47D and MCF7

Yashashwini Subbamanda, Tharunika Subramanian, Aarushi K Zinzuvadia…·Anamika Bhargava

The paper shows that SAK3, a T-type calcium channel enhancer, causes different effects on proliferation and calcium levels in two luminal-A breast cancer cell lines.

DOI 10.1101/2023.11.16.567333

humanbulk RNA-seq

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