Author

Oliver Florey

Babraham InstituteORCID 0000-0002-1075-7424Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 4 Approach:experimental assay· 4 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Joanne DurganiD· 2 shared Abdelmnim RadouaiD· 1 shared Ameetha Ratier· 1 shared Camila Figueiredo PinzaniD· 1 shared Carmen GarridoiD· 1 shared Carolina BifanoiD· 1 shared Caroline Patini RezendeiD· 1 shared Caroline TruntzeriD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCell Biology

Joanne DurganORCID

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4 papers

Recent·Most cited

Cell BiologybioRxivPreprintJul 8, 2026

CASM regulates p62/KEAP1/NRF2 antioxidant responses to lysosome damage

Yasmeen Safayd, Karen E. Anderson, Sophie Blagg…·Oliver Florey

This study identifies CASM as a regulator of antioxidant responses to lysosome damage by activating the p62/KEAP1/NRF2 pathway.

1 citation

proteomicsexperimental assay

𝕏 PostBluesky

Cell BiologybioRxivPreprintJan 24, 2026

CASM potentiates STING-driven NFκB signaling in immune cells

Isis Benoit-Lizon, Cassandre Pignol, Kirsty M. Hooper…·Lionel Apétoh

The paper investigates the role of CASM in STING signaling, finding that CASM enhances NFκB-driven TNF production while autophagy exerts negative feedback on STING pathways.

DOI 10.64898/2026.01.21.700774

mouseproteomics

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ImmunologybioRxivPreprintMar 25, 2025

RAB5c controls the assembly of non-canonical autophagy machinery to promote phagosome maturation and microbicidal function of macrophages

Edismauro Garcia Freitas Filho, Isabella Zaidan, Marlon Fortes-Rocha…·Larissa D. Cunha

This study identifies RAB5c's role in regulating non-canonical autophagy machinery to enhance phagosome maturation and microbial killing by macrophages.

2 citations

mouseproteomics

𝕏 PostBluesky

Cell BiologybioRxivPreprintOct 22, 2024

A distinctive PI(4,5)P2 compartment forms during entosis and related engulfment processes

Joanne Durgan, Katherine Sloan, Marie‐Charlotte Domart…·Oliver Florey

The paper identifies a unique PI(4,5)P2-positive compartment formed during entosis and related engulfment processes, distinct from phagosomes and macropinosomes.

DOI 10.1101/2024.10.22.619613

humanexperimental assay

𝕏 PostBluesky