Cell BiologybioRxiv
Screening the human druggable genome identifies ABHD17B as an anti-fibrotic target in hepatic stellate cells
Wenyang Li, Robert P. Sparks, Cheng Sun…·Alan C. Mullen
The paper identifies ABHD17B as a therapeutic target for liver fibrosis by showing its depletion inactivates hepatic stellate cells and reduces fibrosis in mice.
DOI 10.1038/s41467-025-56900-z