Djamal Brahim Belhaouari

This study identifies ZW-2038, a hydroxypyridone-3-carboxamide analog, as an antiviral lead against orthopoxviruses with low micromolar potency and selectivity in human fibroblasts and organoid models.

This study identifies ciclopirox as an antiviral agent that suppresses poxvirus replication by targeting host iron metabolism.

This study shows that Vaccinia virus increases ACLY phosphorylation via VGF-EGFR-Akt signaling, enhancing lipid synthesis and viral replication.